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    Please use this identifier to cite or link to this item: http://nccur.lib.nccu.edu.tw/handle/140.119/110179

    Title: Resveratrol attenuates cortical neuron activity: roles of large conductance calcium-activated potassium channels and voltage-gated sodium channels
    Authors: 詹銘煥
    Wang, Ya-Jean;Chan, Ming-Huan;Chen, Linyi;Wu, Sheng-Nan;Chen, Hwei-Hisen
    Contributors: 神科所
    Keywords: Resveratrol;BKCa channel;Sodium channel;Action potential;Firing rate
    Date: 2016-05
    Issue Date: 2017-06-05 14:44:31 (UTC+8)
    Abstract: Resveratrol, a phytoalexin found in grapes and red wine, exhibits diverse pharmacological activities. However, relatively little is known about whether resveratrol modulates the ion channels in cortical neurons. The large-conductance calcium-activated potassium channels (BKCa) and voltage-gated sodium channels were expressed in cortical neurons and play important roles in regulation of neuronal excitability. The present study aimed to determine the effects of resveratrol on BKCa currents and voltage-gated sodium currents in cortical neurons.
    Relation: Journal of Biomedical Science, Vol.23, pp.47
    Data Type: article
    DOI 連結: https://dx.doi.org/10.1186/s12929-016-0259-y
    DOI: 10.1186/s12929-016-0259-y
    Appears in Collections:[神經科學研究所 ] 期刊論文

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