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    题名: Evident cognitive impairments in seemingly recovered patients after midazolam-based light sedation during diagnostic endoscopy.
    作者: 楊啟正
    Hsu, Yen-Hsuan
    Lin, Feng-Sheng
    Yang, Chi-Cheng
    Lin, Chih-Peng
    Hua, Mau-Sun
    Sun, Wei-Zen
    贡献者: 心理系
    日期: 2015-06
    上传时间: 2017-09-06 16:29:22 (UTC+8)
    摘要: BACKGROUND/PURPOSE: Midazolam is a widely used sedative agent during colonoscopy, with cognitive toxicity. However, the potential cognitive hazard of midazolam-based light sedation has not been sufficiently examined. We aimed to examine the cognitive safety and vulnerability profile under midazolam light sedation, with a particular focus on individual variations. METHODS: We conducted a prospective case-controlled study in an academic hospital. In total, 30 patients undergoing sedative colonoscopy as part of a health check-up were recruited. Neuropsychological testing on the full cognitive spectrum was evaluated at 15 minutes and 120 minutes after low-dose midazolam administration. The modified reliable change index (RCI) was used for intrapersonal comparisons and controlling for practice effects.
    關聯: Journal of the Formosan Medical Association, Vol.114, No.6, pp.489-497
    数据类型: article
    DOI 連結: https://doi.org/10.1016/j.jfma.2013.07.018
    DOI: 10.1016/j.jfma.2013.07.018
    显示于类别:[心理學系] 期刊論文

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