English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 84662/113307 (75%)
造訪人次 : 22332070      線上人數 : 58
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧:
  • 您可在西文檢索詞彙前後加上"雙引號",以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋,建議至進階搜尋限定作者欄位,可獲得較完整資料
  • 進階搜尋
    請使用永久網址來引用或連結此文件: http://nccur.lib.nccu.edu.tw/handle/140.119/120973


    題名: Mullerian inhibiting substance acts as a motor neuron survival factor in vitro
    作者: Wang, Pei-Yu;Koishi, Kyoko;McGeachie, Andrew B.;Kimber, Michael;MacLaughlin, David T.;Donahoe, Patricia K.;McLennan, Ian S.
    王培育
    Wang, Pei-Yu
    貢獻者: 神科所
    日期: 2005-11
    上傳時間: 2018-11-21 16:23:26 (UTC+8)
    摘要: The survival of motor neurons is controlled by multiple factors that regulate different aspects of their physiology. The identification of these factors is important because of their relationship to motor neuron disease. We investigate here whether Mullerian Inhibiting Substance (MIS) is a motor neuron survival factor. We find that motor neurons from adult mice synthesize MIS and express its receptors, suggesting that mature motor neurons use MIS in an autocrine fashion or as a way to communicate with each other. MIS was observed to support the survival and differentiation of embryonic motor neurons in vitro. During development, male-specific MIS may have a hormone effect because the blood-brain barrier has yet to form, raising the possibility that MIS participates in generating sex-specific differences in motor neurons.
    關聯: Proceedings of the National Academy of Sciences of the United States of America, Vol.102, No.45, pp.16421-16425
    PMID: 16260730
    資料類型: article
    DOI 連結: https://doi.org/10.1073/pnas.0508304102
    DOI: 10.1073/pnas.0508304102
    顯示於類別:[神經科學研究所 ] 期刊論文

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    pnas-0508304102.pdf398KbAdobe PDF29檢視/開啟


    在政大典藏中所有的資料項目都受到原著作權保護.


    社群 sharing

    著作權政策宣告
    1.本網站之數位內容為國立政治大學所收錄之機構典藏,無償提供學術研究與公眾教育等公益性使用,惟仍請適度,合理使用本網站之內容,以尊重著作權人之權益。商業上之利用,則請先取得著作權人之授權。
    2.本網站之製作,已盡力防止侵害著作權人之權益,如仍發現本網站之數位內容有侵害著作權人權益情事者,請權利人通知本網站維護人員(nccur@nccu.edu.tw),維護人員將立即採取移除該數位著作等補救措施。
    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋