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| Title: | 憂鬱不再難治？經顱磁刺激(TMS)在台灣的行動者網絡理論分析
Depression No More Treatment-Resistant? The Transcranial Magnetic Stimulation (TMS) in Taiwan as a Case of Actor-Network Theory |
| Authors: | 袁嘉儀
Yuan, Chia-Yi |
| Contributors: | 陳宗文
Chen, Tzung-Wen
袁嘉儀
Yuan, Chia-Yi |
| Keywords: | 創新擴散
醫療創新
行動者網絡理論
經顱磁刺激術
重鬱症
Diffusion of innovation
Medical innovation
Actor-Network Theory (ANT)
Transcranial magnetic stimulation (TMS)
Major depressive disorder (MDD) |
| Date: | 2024 |
| Issue Date: | 2024-02-01 11:41:20 (UTC+8) |
| Abstract: | 經顱磁刺激（transcranial magnetic stimulation, TMS）是近年來引起關注的新興技術，為人所知的是在神經精神疾病的醫學用途。它逐步購置於不同地區的醫院診所，並有專門化的醫療社群。本研究採取行動者網絡理論（Actor-Network Theory, ANT），分析TMS此一醫療創新在台灣擴散的情形。以技術為中心的視角，我們採用次級資料和深度訪談的質性方法，描述TMS在不同網絡的軌跡，分析關注點和參與行動者，以了解旨趣被促動的轉譯過程。
研究發現，（一）TMS移動於不同網絡，行動者是多重且異質的神經精神科專業，從事研究和治療、來自醫院和診所，有著零散或聚集的聯盟。（二）TMS的軌跡伴隨著關注點位移，從醫學問題移至臨床議題。隨著多重專業加入網絡，創新技術被用來理解和概念化醫療情境的問題是什麼，從而讓多元旨趣被促動並徵召，包含臨床、技術、文化、經濟、制度等。本研究主張，創新擴散無法由專業的價值系統所決定，社會團體和技術文化也無法輕易介入，而是複雜且動態的關係本體，由人與非人行動者共同建構，充滿不確定性。
Transcranial magnetic stimulation (TMS) is an emerging technology that has attracted attention in recent years for its medical use in neuropsychiatric diseases. It has been gradually purchased in hospitals and clinics in different regions and form medical community dedicatedly. This study use Actor-Network Theory (ANT) to analyze the diffusion of TMS, a medical innovation, in Taiwan. From the technology-centered view, we use a qualitative method including secondary data and in-depth interviews to describe the trajectories of TMS in terms of matter of conccern and involved actors in different networks, in order to understand how interests be enacted through the process of translation.
The study found that (1) TMS moves in different networks, and involed actors are multiple and heterogeneous neuropsychiatric specialties, doing research and therapy, from hospitals and clinics, with scattered or aggregated alliances. (2) The trajectory of TMS is accompanied by the deplacement in matter of concern, from medical problems to clinical issues. When these multiple specialties involve in networks, innovative technology is used to understand and conceptualize what the problems are in medical condition, thus diverse interests, that is clinical, technological, cultural, economic, institutional, are enacted and enrolled in. This study contends that the diffusion of innovation does not solely depend on professional value system, nor can social group or technical culture easily intervene, but is a complex and dynamic relational ontology, jointly constructed by human and non-human actors, thus full of uncertainty. |
| Reference: | 中文書目
Latour, Bruno、V. A. Lépinay著，陳榮泰、伍啟鴻譯，2017，《激情的經濟學：我們從未理性過？塔德人類學的經濟解讀》。台灣：群學。
Latour, Bruno著，伍啟鴻、陳榮泰譯，2016，《巴斯德的實驗室：細菌的戰爭與和平》。台灣：群學。
─────，余曉嵐、林文源、許全義譯，2012，《我們從未現代過》。台灣：群學。
─────，林宗德譯，2004。〈給我一個實驗室，我將舉起全世界〉。頁219-263，收錄於吳嘉苓、傅大為、雷祥麟編，《科技渴望社會》。台灣：群學。
Rogers, Everett M. 著，唐錦超譯，2006，《創新的擴散》。台灣：遠流。
台灣臨床TMS腦刺激學會，2021。《憂鬱是因為你的大腦生病了：照照磁波，活化腦區，解憂抗鬱新方向》。台灣：世茂。
─────，2023，〈重複經顱磁刺激術(rTMS)臨床使用立場聲明〉。台灣臨床TMS腦刺激學會，4月24日。
吳佳璇、林信男，2001，〈療效不佳的憂鬱症〉。《當代醫學》，(330)，291–293。
李正達，2012，《抗憂鬱藥物難治型憂鬱症之中樞致病機轉探討–腦神經造影及重覆透顱磁刺激研究》。台北：國立陽明大學腦科學研究所博士論文。
─────，2023a，〈主編序〉。頁x–xi，收錄於李正達編，《腦神經刺激治療精神疾病rTMS完全攻略》。台灣：合記。
─────，2023b，〈對抗鬱劑治療頑固的鬱症治療建議〉。頁183–195，收錄於李明濱編，《建立整合性憂鬱症防治共同照護網模式》，苗栗：國家衛生研究院。
李晉邦，2020，〈精神醫學的絕地武士－電痙攣〈ECT〉治療〉。頁9–10，收錄於臺灣憂鬱症防治協會編，《腦刺激術-rTMS、tDCS、ECT在憂鬱症上的應用》，《臺灣憂鬱症防治協會通訊》第十九卷第二期。
沈武典，2007，《21世紀臨床精神藥物學（二版）》。台灣：合記。
林宙晴，2022，〈推薦序1〉。頁i，收錄於黃英儒編，《非侵入性腦刺激術-基礎、臨床與研究》。台灣：合記。
林皇利，2020，〈談重複經顱磁刺激（rTMS）在憂鬱症的應用〉。頁2–4，收錄於臺灣憂鬱症防治協會編，《腦刺激術-rTMS、tDCS、ECT在憂鬱症上的應用》，《臺灣憂鬱症防治協會通訊》第十九卷第二期。
洪嘉均、周伯翰，2014，經顱磁刺激於憂鬱症患者之維持療效研究。（國軍退除役官兵輔導委員會 TCVGH-1034002B）。台中：臺中榮民總醫院精神科。
倪信章等，2016，重複性經顱磁刺激術對兒童青少年自閉症患者社交能力改變的初探(第一年)。（科技部 MOST105-2628-B182A-005-MY3）。桃園：長庚醫療財團法人兒童心智科。
張家銘，2019，〈理事長的話〉。頁2–3，收錄於臺灣憂鬱症防治協會編，《臺灣憂鬱症防治協會通訊》第十八卷第一期。
張維紘等，2015，針對無藥物使用之強迫症患者其腦功能連結及相關神經荷爾蒙研究---比較重複腦部磁脈衝波治療術及藥物治療成效(第一年)。（科技部 MOST104-2314-B006-054-MY3）。台南：國立成功大學醫學系精神科。
莊雯莉，2022，〈經顱磁刺激的基本原理〉。頁5–16，收錄於黃英儒編，《非侵入性腦刺激術-基礎、臨床與研究》。台灣：合記。
陳宗文，2012，〈社會／創新如何可能？一種塔德式的理解〉。《政治與社會哲學評論》，(41)，153 – 203。
黃智佳，2008，《重覆透顱磁刺激對憂鬱症患者療效的預測因子探討》。台北：國立陽明大學腦科學研究所博士論文。
楊延光、鄭淑惠，2003，《全方位憂鬱症防治手冊》。台北：張老師文化。
葉啓斌、柯慧貞、陸汝斌，1999，〈Venlafaxine與Imipramine治療重度鬱症之比較〉。《台灣精神醫學》，13(1)，44 – 53。
謝文菁，2023，〈憂鬱症治療新模式：降低藥物的身心不適感受〉，《臺灣憂鬱症防治協會通訊》，22(3)，3。
藍祚鴻、陳展航、洪嘉均，2012，合併藥物及經顱磁刺激治療重鬱症患者之療效評估。（國軍退除役官兵輔導委員會 TCVGH-1014001B）。台中：臺中榮民總醫院精神科。
蘇東平等，2002，重覆透顱磁刺激於精神疾病之應用。（國軍退除役官兵輔導委員會 VAC91-237）。台中：臺北榮民總醫院精神病部。
─────，2012，〈總策畫序－躁鬱症是腦部神經激素分泌失調的疾病之一〉。頁10–13，收錄於蘇東平編，《走進躁鬱世界》。台北：原水文化。
─────，2023，〈推薦序：台灣rTMS發展之簡史〉。頁vi-vii，收錄於李正達編，《腦神經刺激治療精神疾病rTMS完全攻略》。台灣：合記。
蘇冠賓等，2012，經顱磁刺激之神經、心理及生物效應研究：以腦磁刺激療法探討憂鬱症之身心介面(第一年)。（財團法人國家衛生研究院 NHRI-EX101-10144NI）。台中：中國醫藥大學神經科學與認知科學研究所。
英文書目
Bijker, Wiebe E., 1997, Of bicycles, bakelites, and bulbs: Toward a theory of sociotechnical change. MIT press.
Blume, Stuart S., 2013, “Medical innovations: Their diffusion, adoption, and critical interrogation.” Sociology Compass 7(9): 726-737.
Burt, Ronald S. “Social contagion and innovation: Cohesion versus structural equivalence.” American journal of Sociology 92.6 (1987): 1287-1335.
Callon, Michel, 1984, “Some elements of a sociology of translation: domestication of the scallops and the fishermen of St Brieuc Bay.” The sociological review 32(1_suppl): 196-233.
Chen, Yang-Chieh Brian et al., 2023, “Trajectory of changes in depressive symptoms after acute repetitive transcranial magnetic stimulation: a meta-analysis of follow-up effects.” Asian Journal of Psychiatry 88, 103717.
Chou, Po-Han et al., 2021, “Personalization of repetitive transcranial magnetic stimulation for the treatment of major depressive disorder according to the existing psychiatric comorbidity.” Clinical Psychopharmacology and Neuroscience 19(2): 190.
Chou, Po-Han et al., 2023, “NIRS-aided differential diagnosis among patients with major depressive disorder, bipolar disorder, and schizophrenia.” Journal of Affective Disorders 341: 366-373.
Clarke, Adele et al., 2003, “Biomedicalization: Technoscientific Transformations of Health, Illness, and U.S. Biomedicine.” American Sociological Review (68)2: 161–94.
Cole, Eleanor J. et al., 2020, “Stanford accelerated intelligent neuromodulation therapy for treatment-resistant depression.” American Journal of Psychiatry 177(8): 716-726.
Coleman, James, Elihu Katz and Herbert Menzel, 1957, “The diffusion of an innovation among physicians.” Sociometry 20(4): 253-270.
Coleman, James, Herbert Menzel and Elihu Katz, 1959, “Social processes in physicians' adoption of a new drug.” Journal of chronic diseases 9(1): 1-19.
Conrad, Peter, 1992, “Medicalization and social control”. Annual review of Sociology (18)1: 209-232.
Consoli, Davide and Andrea Mina, 2009, “An evolutionary perspective on health innovation systems.” Journal of evolutionary economics 19: 297-319.
Dunner, David L., 2013, “Treatment-resistant depression.” 臺灣精神醫學 27(2): 110-120+.
Eldaief, Mark C., Daniel Z. Press and Alvaro Pascual-Leone, 2013, “Transcranial magnetic stimulation in neurology: a review of established and prospective applications.” Neurology: Clinical Practice 3(6): 519-526.
Erickson‐Davis, Cordelia, 2012, “Ethical concerns regarding commercialization of deep brain stimulation for obsessive compulsive disorder.” Bioethics, 26(8): 440-446.
Faulkner, Alex, 2008, Medical technology into healthcare and society: A sociology of devices, innovation and governance. Springer.
Fitzgerald, Paul B. and Z. Jeff Daskalakis, 2022, rTMS Treatment for Depression: A Practical Guide. Springer.
Gelijns, Annetine and Nathan Rosenberg, 1994, “The dynamics of technological change in medicine.” Health affairs 13(3): 28-46.
George, Mark S., Terence A. Ketter and Robert M. Post, 1993, “SPECT and PET imaging in mood disorders.” The Journal of clinical psychiatry 54: 6-13.
Hallett, Mark, 2007, “Transcranial magnetic stimulation: a primer.” Neuron 55(2): 187-199.
Huang, Chih-Chia, Tung-Ping Su and I-Hua Wei, 2005, “Repetitive transcranial magnetic stimulation for treating medication-resistant depression in Taiwan: a preliminary study.” Journal of the Chinese Medical Association 68(5): 210-215.
Huang, Ying-Zu et al.,2005, “Theta burst stimulation of the human motor cortex.” Neuron 45(2): 201-206.
Jasanoff, Sheila and Sang-Hyun Kim, 2009, “Containing the atom: Sociotechnical imaginaries and nuclear power in the United States and South Korea.” Minerva 47: 119-146.
Jasanoff, Sheila and Sang-Hyun Kim, 2015, Dreamscapes of modernity: Sociotechnical imaginaries and the fabrication of power. University of Chicago Press.
Katz, Elihu, Martin L. Levin and Herbert Hamilton, 1963, “Traditions of research on the diffusion of innovation.” American sociological review, 237-252.
Lakoff, Andrew, 2004, “The anxieties of globalization: antidepressant sales and economic crisis in Argentina.” Social Studies of Science 34(20): 247-269.
Lan, Tsuo-Hung, 2015, “The Application of Near-infrared Spectroscopy in Psychiatry.” 臺灣精神醫學 29(2): 80-88.
Latour, Bruno et al., 2012. “‘The whole is always smaller than its parts’–a digital test of G abriel T ardes' monads.” The British journal of sociology 63(4): 590-615.
Latour, Bruno, 1996, Aramis, or the Love of Technology. Harvard University Press.
Latour, Bruno, 2007, Reassembling the social: An introduction to actor-network-theory. Oup Oxford.
Lee, Min-Soo, 2016, “Pharmacogenetics of Antidepressants: Is There a Magic Bullet for Treating Depression?.” 臺灣精神醫學 30(2): 79-90+.
Li, Cheng-Ta et al., 2010a, “Antidepressant mechanism of add-on repetitive transcranial magnetic stimulation in medication-resistant depression using cerebral glucose metabolism.” Journal of affective disorders 127(1-3): 219-229.
Li, Cheng-Ta et al., 2010b, “Structural and cognitive deficits in remitting and non-remitting recurrent depression: a voxel-based morphometric study.” Neuroimage 50(1): 347-356.
Li, Cheng-Ta et al., 2012, “Association between antidepressant resistance in unipolar depression and subsequent bipolar disorder: cohort study.” The British Journal of Psychiatry 200(1): 45-51.
Li, Cheng-Ta et al., 2013, “Impaired prefronto-thalamic functional connectivity as a key feature of treatment-resistant depression: a combined MEG, PET and rTMS study.” PLoS One 8(8): e70089.
Li, Cheng-Ta et al., 2014, “Efficacy of prefrontal theta-burst stimulation in refractory depression: a randomized sham-controlled study.” Brain 137(7): 2088-2098.
Li, Cheng-Ta et al., 2015, “Prefrontal glucose metabolism in medication-resistant major depression.” The British Journal of Psychiatry 206(4): 316-323.
Li, Cheng-Ta et al., 2023, “Prediction of antidepressant responses to non-invasive brain stimulation using frontal electroencephalogram signals: Cross-dataset comparisons and validation.” Journal of Affective Disorders 343: 86-95.
Li, Cheng-Ta, 2021, “Taiwanese Expert Consensus of Repetitive Transcranial Magnetic Stimulation (rTMS) on Depression Treatment.” Taiwanese Society of Biological Psychiatry and Neuropsychopharmacology, 1-7. (Unpublished)
─────, 2023, “Overview of treatment-resistant depression.” Progress in brain research 278: 1-23.
Lin, Chih-Kuang et al., 2008, “Add-on Theta Burst Stimulation for Treatment-resistant Depression with Migraine.” 臺灣精神醫學 22(4): 322-326.
Marsden, Peter V. and Joel Podolny, 1990, “Dynamic analysis of network diffusion processes.” Social networks through time, 197-214.
Mina, Andrea et al., 2007, “Mapping evolutionary trajectories: Applications to the growth and transformation of medical knowledge.” Research policy 36(5): 789-806.
Mokyr, Joel, 1998, “Induced technical innovation and medical history: an evolutionary approach.” Journal of Evolutionary Economics 8(2): 119-137.
Nelson, Richard R. and Sidney G. Winter, 1977, “In search of a useful theory of innovation.” Innovation, economic change and technology policies 6(1): 215-245.
Ni, Hsing-Chang et al., 2017, “The impact of single session intermittent theta-burst stimulation over the dorsolateral prefrontal cortex and posterior superior temporal sulcus on adults with autism spectrum disorder.” Frontiers in neuroscience 11: 255.
Pickersgill, Martyn, 2011, “‘Promising’therapies: Neuroscience, clinical practice, and the treatment of psychopathy.” Sociology of Health & Illness 33(3): 448-464.
Pickersgill, Martyn, 2013, “The social life of the brain: Neuroscience in society.” Current Sociology 61(3): 322-340.
Rose, Nikolas, 2007, The Politics of Life itself: Biomedicine, Power, and Subjectivity in the Twenty-first Century. Princeton University Press.
Su, Tung-Ping, Chih-Chia Huang and I-Hua Wei, 2005, “Add-on rTMS for medication-resistant depression: a randomized, double-blind, sham-controlled trial in Chinese patients.” Journal of Clinical Psychiatry 66(7): 930-937.
Valente, Thomas W., 1996, “Social network thresholds in the diffusion of innovations.” Social networks 18(1): 69-89.
Van den Bulte, Christophe, and Gary L. Lilien, 2001, “Medical innovation revisited: Social contagion versus marketing effort.” American journal of sociology 106(5): 1409-1435.
Wang, Hsiao-Han et al., 2022, “Ten-year trends in depression care in Taiwan.” Journal of the Formosan Medical Association 121(10): 2001-2011.
Williams, Nolan R. et al., 2018, “High-dose spaced theta-burst TMS as a rapid-acting antidepressant in highly refractory depression.” Brain 141(3): e18-e18.
Wu, Chia-Cheng et al., 2010, “Theta-burst repetitive transcranial magnetic stimulation for treatment-resistant obsessive-compulsive disorder with concomitant depression.” The Journal of clinical psychiatry 71(4): 20928.
Wu, Yi-Cheng et al., 2011, “Predictors of Non-remission for Antidepressant Treatment among the Elders with Major Depressive Disorder: A Preliminary Open-label Study.” 臺灣精神醫學 25(2): 99-105.
Zhang, Jing Hua et al., 2014, “Hospital ownership and drug utilization under a global budget: a quantile regression analysis.” International Health 6(1): 62-69.
網路資料
中央健康保險署，2019。〈健保署依法調整藥價，願積極與藥界檢討DET之計算公式〉。https://www.mohw.gov.tw/cp-16-46830-1.html。取用日期：2023年8月27日。
友信．整合傳播部企劃製作，2023。〈「憂鬱世代新希望」精神科權威：李正達X鄭晴醫師專訪，憂鬱症治療突破deepTMS〉。取自：https://www.cw.com.tw/article/5126770。取用日期：2024年1月19日。
台灣科技媒體中心，2019。〈百憂解退出台灣市場，引發後續效應之專家回應〉。https://smctw.tw/5032/。取用日期：2023年8月27日。
李正達，2018，〈台北榮總精神醫學部「活化腦區不再憂鬱-重覆經顱磁刺激(rTMS)」新聞稿〉。https://www.vghtpe.gov.tw/vghtpe/News!one.action?nid=4634&gcode=A05。取用日期：2022年8月7日。
張銘坤，2019。〈憂鬱症老藥百憂解4月停供 國內仍有14家生產同成分藥〉。中央通訊社。https://www.cna.com.tw/news/firstnews/201903180182.aspx。取用日期：2023年8月27日。
陳稚華，2019，〈「百憂解」退出台灣背後隱藏的危機〉。信媒體。http://www.irpma.org.tw/zh_TW/education2_content/id/653。取用日期：2023年8月27日。
黃緒勳，2021，〈藥物之外的好選擇重覆式經顱磁刺激治療系統〉。TNN台灣地方新聞。http://tn.news.tnn.tw/news.html?c=&id=151935。取用日期：2022年12月18日。
臺灣憂鬱症防治協會，2020，〈憂鬱症治療指南〉。https://www.depression.org.tw/knowledge/info.asp?/96.html。取用日期：2022年8月6日。
鍾佩錦，2019。〈不堪健保砍價…百憂解退出台灣後，這抗生素也將停止供貨〉。https://www.edh.tw/article/21358。取用日期：2023年8月27日。 |
| Description: | 碩士
國立政治大學
社會學系
109254006 |
| Source URI: | http://thesis.lib.nccu.edu.tw/record/#G0109254006 |
| Data Type: | thesis |
| Appears in Collections: | [社會學系] 學位論文
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