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    Please use this identifier to cite or link to this item: http://nccur.lib.nccu.edu.tw/handle/140.119/63785

    Title: Accelerated Proton-Echo-Planar-Spectroscopic-Imaging using GRAPPA with a 32-Channel Phase Array Coil
    Authors: 蔡尚岳
    Tsai, Shang-Yueh;Otazo, Ricardo;Posse, Stefan;Lin, Yi-Ru;Chung, Hsiao-Wen;Wald, Lawrence L.;Wiggins, Graham C.;Lin, Fa-Hsuan
    Contributors: 應物所
    Keywords: proton echo planar spectroscopic imaging;PEPSI;MR spectroscopic imaging;parallel MRI;32
    Date: 2008.04
    Issue Date: 2014-02-11 14:02:20 (UTC+8)
    Abstract: Parallel imaging has been demonstrated to reduce the encoding time of MR spectroscopic imaging (MRSI). Here we investigate up to 5-fold acceleration of 2D proton echo planar spectroscopic imaging (PEPSI) at 3T using generalized autocalibrating partial parallel acquisition (GRAPPA) with a 32-channel coil array, 1.5 cm3 voxel size, TR/TE of 15/2000 ms, and 2.1 Hz spectral resolution. Compared to an 8-channel array, the smaller RF coil elements in this 32-channel array provided a 3.1-fold and 2.8-fold increase in signal-to-noise ratio (SNR) in the peripheral region and the central region, respectively, and more spatial modulated information. Comparison of sensitivity-encoding (SENSE) and GRAPPA reconstruction using an 8-channel array showed that both methods yielded similar quantitative metabolite measures (P > 0.1). Concentration values of N-acetyl-aspartate (NAA), total creatine (tCr), choline (Cho), myo-inositol (mI), and the sum of glutamate and glutamine (Glx) for both methods were consistent with previous studies. Using the 32-channel array coil the mean Cramer–Rao lower bounds (CRLB) were less than 8% for NAA, tCr, and Cho and less than 15% for mI and Glx at 2-fold acceleration. At 4-fold acceleration the mean CRLB for NAA, tCr, and Cho was less than 11%. In conclusion, the use of a 32-channel coil array and GRAPPA reconstruction can significantly reduce the measurement time for mapping brain metabolites. Magn Reson Med 59:989–998, 2008. © 2008 Wiley-Liss, Inc.
    Relation: Magn Reson Med, 59(5), 989-998
    Data Type: article
    Appears in Collections:[應用物理研究所 ] 期刊論文

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