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    題名: Clinical and biochemical characteristics of women with menstrual disturbance
    作者: Shen, S.-Y.;Huang, S.-Y.;Hsieh, C.-H.;Hsu, M.-I.;Cheng, Chih Yu;Hsu, C.-S.
    成之約
    貢獻者: 勞工所
    關鍵詞: androgen;androstenedione;cholesterol;ferritin;insulin;low density lipoprotein;luteinizing hormone;prolactin;testosterone;adult;amenorrhea;article;cholesterol blood level;controlled study;female;human;hyperandrogenism;insulin resistance;lipid analysis;major clinical study;menstrual cycle;menstruation disorder;metabolic disorder;metabolic parameters;metabolic syndrome X;oligomenorrhea;prolactin blood level;retrospective study
    日期: 2014-06
    上傳時間: 2015-06-16 17:34:11 (UTC+8)
    摘要: Objective: Menstrual irregularity is one of the major complaints in women of reproductive age. The aim of this study was to evaluate the complications in women with different menstrual disturbances. Materials and methods: This is a retrospective study. A total of 576 women were screened first, and 470 women were included later [257 women with oligo/amenorrhea (149 hyperandrogenic and 108 nonhyperandrogenic women) and 213 normocyclic controls]. Endocrine and metabolic parameters and insulin resistance were compared among different menstrual patterns. Results: The average duration of menstrual cycle length was positively correlated with age, levels ofandrogens and prolactin, lipid profiles, and the parameters of insulin resistance. Hyperandrogenic women with amenorrhea had higher levels of androgens and more lipid profiles disorders than hyperandrogenic women with oligomenorrhea. However, nonhyperandrogenic women with amenorrhea had a degree of insulin resistance and metabolic disturbance similar to that of nonhyperandrogenic women with oligomenorrhea. Interestingly, for women with normal prolactin levels, serum prolactin levels were significantly lower in amenorrhea than oligomenorrhea in both hyperandrogenic and nonhyperandrogenic groups. Conclusion: The degree of menstrual disturbances does not correlate with the severity of insulin resistance and metabolic disturbances in women without excess levels of androgen. For women withnormal prolactin levels, amenorrheic patients had significantly lower serum prolactin levels than oligomenorrheic patients. © 2014.
    關聯: Taiwanese Journal of Obstetrics and Gynecology, 53(2), 178-182
    資料類型: article
    DOI: http://dx.doi.org/10.1016/j.tjog.2014.04.009
    顯示於類別:[勞工研究所] 期刊論文

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