English  |  正體中文  |  简体中文  |  Post-Print筆數 : 11 |  Items with full text/Total items : 89672/119493 (75%)
Visitors : 23942971      Online Users : 140
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    政大機構典藏 > 理學院 > 心理學系 > 期刊論文 >  Item 140.119/76769
    Please use this identifier to cite or link to this item: http://nccur.lib.nccu.edu.tw/handle/140.119/76769


    Title: Semantic memory deficits in low-educated patients with Alzheimer's disease
    Authors: Yang, C.-C.;Hua, M.-S.;Chiu, M.-J.;Chen, S.-T.;Yip, P.-K.;Chen, T.-F.;Wu, C.-H.;Wen, M.-C.;Tseng, H.-H.;Chu, Y.-C.;Wang, C.-Y.;Tu, Pei Chong
    涂珮瓊
    Contributors: 心理系
    Keywords: adult;aged;Alzheimer disease;amnesia;analysis of covariance;analysis of variance;article;controlled study;dementia;disease severity;education;human;major clinical study;neurologic examination;recall;recognition;semantics;Aged;Case-Control Studies;Dementia;Educational Status;Humans;Mental Recall;Neuropsychological Tests;Semantics;Severity of Illness Index
    Date: 2006-11
    Issue Date: 2015-07-21 15:34:45 (UTC+8)
    Abstract: Background/Purpose: Although a deficit of semantic memory is evident in the dementia of the Alzheimer's type (DAT), the underlying neuropsychologic mechanism remains controversial. Breakdown of the semantic network during the course of DAT and an inability to access semantic information have been postulated as possible explanations, but supporting data are limited, particularly in low-educated patients. This study examined semantic memory in low-educated patients with different degrees of dementia severity. Methods: In total, 197 adult subjects were recruited, including 165 DAT patients and 32 normal controls. Subjects were divided into four subgroups according to their dementia severity. All subjects completed an episodic memory task, the Six-Object Memory Test, and semantic memory tasks including the Object Naming Test, the Remote Memory Test and the Semantic Association of Verbal Fluency Test. One-way ANOVA and ANCOVA with a post hoc Scheffe's procedure were used to evaluate differences between groups. Results: All patients, irrespective of the degree of dementia, showed impaired performance on the Six-Object Memory Test [F(4, 163)=69.95, p<0.0001 for immediate recall; F(4, 163)=41.34, p<0.0001 for delayed recall]. On the semantic memory tasks, patients with moderate to severe dementia showed impaired performances on the Object Naming Test [F(4, 180)=28.25, p<0.0001] and the Remote Memory Test [F(4, 167)=26.22, p<0.0001 for recall; F(4, 167)=34.80, p<0.0001 for recognition], while all patients performed defectively on the Semantic Association of Verbal Fluency Test [F(4, 194)=70.43, p<0.0001]. Conclusion: Our results thus partially support the hypotheses that a loss of semantic structure and an inability to access semantic knowledge occur in the pathogenesis of DAT. ©2006 Elsevier & Formosan Medical Association.
    Relation: Journal of the Formosan Medical Association, 105(11), 926-935
    Data Type: article
    DOI 連結: http://dx.doi.org/10.1016/S0929-6646(09)60178-9
    DOI: 10.1016/S0929-6646(09)60178-9
    Appears in Collections:[心理學系] 期刊論文

    Files in This Item:

    File Description SizeFormat
    926-935.pdf277KbAdobe PDF467View/Open


    All items in 政大典藏 are protected by copyright, with all rights reserved.


    社群 sharing

    著作權政策宣告
    1.本網站之數位內容為國立政治大學所收錄之機構典藏,無償提供學術研究與公眾教育等公益性使用,惟仍請適度,合理使用本網站之內容,以尊重著作權人之權益。商業上之利用,則請先取得著作權人之授權。
    2.本網站之製作,已盡力防止侵害著作權人之權益,如仍發現本網站之數位內容有侵害著作權人權益情事者,請權利人通知本網站維護人員(nccur@nccu.edu.tw),維護人員將立即採取移除該數位著作等補救措施。
    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback