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    政大機構典藏 > 理學院 > 資訊科學系 > 期刊論文 >  Item 140.119/97014
    Please use this identifier to cite or link to this item: http://nccur.lib.nccu.edu.tw/handle/140.119/97014

    Title: TCS: a web server for multiple sequence alignment evaluation and phylogenetic reconstruction
    Authors: 張家銘
    Chang, Jia-Ming;Tommaso, Paolo Di;Lefort, Vincent;Gascuel, Olivier;Notredame, Cedric
    Contributors: 資科系
    Date: 2015-07
    Issue Date: 2016-05-30 17:24:39 (UTC+8)
    Abstract: This article introduces the Transitive Consistency Score (TCS) web server; a service making it possible to estimate the local reliability of protein multiple sequence alignments (MSAs) using the TCS index. The evaluation can be used to identify the aligned positions most likely to contain structurally analogous residues and also most likely to support an accurate phylogenetic reconstruction. The TCS scoring scheme has been shown to be accurate predictor of structural alignment correctness among commonly used methods. It has also been shown to outperform common filtering schemes like Gblocks or trimAl when doing MSA post-processing prior to phylogenetic tree reconstruction. The web server is available from http://tcoffee.crg.cat/tcs
    Relation: Nucleic Acids Research, Vol.43, No.W1, pp.W3-6
    Data Type: article
    DOI 連結: http://dx.doi.org/10.1093/nar/gkv310
    DOI: 10.1093/nar/gkv310
    Appears in Collections:[資訊科學系] 期刊論文

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