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    政大機構典藏 > 商學院 > 統計學系 > 期刊論文 >  Item 140.119/18168
    Please use this identifier to cite or link to this item: http://nccur.lib.nccu.edu.tw/handle/140.119/18168

    Title: Testing the Nonrandomness of Choromosomal Breakpoints Using Highest Observed Breakages
    Authors: 侯家鼎;江振東;戴政
    Hou, Chia-Ding;Chiang, Jengtung;John Jen Tai
    Date: 1999-04
    Issue Date: 2008-12-19 14:52:27 (UTC+8)
    Abstract: To determine whether a chromosomal band is a fragile site rather than a spontaneous breakpoint, an essential step is to test the nonrandomness of breakage at the region. In this paper, the nonapplicability of the testing procedure introduced by Bohm et al. is discussed, and a new detection procedure is proposed. This new procedure considers the relations of one site with the others, and can be applied to tests of the nonrandomness of breakpoints under either the proportional probability model, or the equiprobability model. A data set for Chinese patients with colorectal carcinoma is analyzed as an illustration of the proposed method.
    Relation: Human Genetics, 104(4), 350-355
    Data Type: article
    DOI 連結: http://dx.doi.org/10.1007/s004390050965
    DOI: 10.1007/s004390050965
    Appears in Collections:[統計學系] 期刊論文

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