政大機構典藏-National Chengchi University Institutional Repository(NCCUR):Item 140.119/59068
English  |  正體中文  |  简体中文  |  Post-Print筆數 : 27 |  全文笔数/总笔数 : 112704/143671 (78%)
造访人次 : 49721933      在线人数 : 726
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻
    政大機構典藏 > 理學院 > 心理學系 > 期刊論文 >  Item 140.119/59068


    请使用永久网址来引用或连结此文件: https://nccur.lib.nccu.edu.tw/handle/140.119/59068


    题名: Attention-deficit/hyperactivity disorder with obstructive sleep apnea: a treatment outcome study
    作者: Chen, N.H.
    Huang, Y.S
    Guilleminault, C.
    Li, H.Y.
    Yang, C.M.
    Wu, Y.Y.
    楊建銘
    贡献者: 國立政治大學心理學系
    关键词: Keywords Attention-deficit/hyperactivity disorder;Methylphenidate;Adenotonsillectomy;Obstructive sleep apnea;Polysomnography;Outcome
    日期: 2007
    上传时间: 2013-08-15 09:42:41 (UTC+8)
    摘要: Background
    Children diagnosed with attention-deficit/hyperactivity disorder (ADHD), based on Diagnostic and Statistical Manual of Mental Disorders, Fourth edition (DSM-IV) criteria, may also have obstructive sleep apnea (OSA), but it is unclear whether treating OSA has similar results as methylphenidate (MPH), a commonly used treatment for ADHD.

    Methods
    This study enrolled 66 school-age children, referred for and diagnosed with ADHD, and 20 healthy controls. Polysomnography (PSG) performed after ADHD diagnosis showed the presence of mild OSA. After otolaryngological evaluation, parents and referring physicians of the children could select treatment of ADHD with MPH, treatment of OSA with adenotonsillectomy or no treatment. Systematic follow-up was performed six months after initiation of treatment, or diagnosis if no treatment. All children had pre- and post-clinical interviews; pediatric, neurologic, psychiatric and neurocognitive evaluation; PSG; ADHD rating scale, child behavior checklist (CBCL) filled out by parents and teacher; test of variables of attention (TOVA); and the quality of life in children with obstructive sleep disorder questionnaire (OSA-18).

    Results
    ADHD children had an apnea-hypopnea index (AHI) > 1 < 5 event/hour; 27 were treated with MPH, 25 had adenotonsillectomy, and 14 had no treatment. The surgical and MPH groups improved more than the non-treatment group. When comparing MPH to post-surgery, the PSG and questionnaire sleep variables, some daytime symptoms (including attention span) and TOVA subscales (impulse control, response time and total ADHD score) improved more in the surgical group than the MPH group. The surgical group had an ADHD total score of 21.16 ± 7.13 on the ADHD rating scale (ADHD-RS) post-surgery compared to 31.52 ± 7.01 pre-surgery (p = 0.0001), and the inattention and hyperactivity subscales were also significantly lower (p = 0.0001). Finally, the results were significantly different between surgically and MPH-treated groups (ADHD-RS p = 0.007). The surgical group also had a TOVA ADHD score lower than −1.8 and close to those obtained in normal controls.

    Conclusion
    A low AHI score of > 1 considered abnormal is detrimental to children with ADHD. Recognition and surgical treatment of underlying mild sleep-disordered breathing (SDB) in children with ADHD may prevent unnecessary long-term MPH usage and the potential side effects associated with drug intake.
    關聯: Sleep Medicine, 8, 18-30
    数据类型: article
    DOI 連結: http://dx.doi.org/10.1016/j.sleep.2006.05.016
    DOI: 10.1016/j.sleep.2006.05.016
    显示于类别:[心理學系] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    Attention-deficithyperactivity.pdf168KbAdobe PDF21208检视/开启


    在政大典藏中所有的数据项都受到原著作权保护.


    社群 sharing

    著作權政策宣告 Copyright Announcement
    1.本網站之數位內容為國立政治大學所收錄之機構典藏，無償提供學術研究與公眾教育等公益性使用，惟仍請適度，合理使用本網站之內容，以尊重著作權人之權益。商業上之利用，則請先取得著作權人之授權。
    The digital content of this website is part of National Chengchi University Institutional Repository. It provides free access to academic research and public education for non-commercial use. Please utilize it in a proper and reasonable manner and respect the rights of copyright owners. For commercial use, please obtain authorization from the copyright owner in advance.

    2.本網站之製作，已盡力防止侵害著作權人之權益，如仍發現本網站之數位內容有侵害著作權人權益情事者，請權利人通知本網站維護人員(nccur@nccu.edu.tw)，維護人員將立即採取移除該數位著作等補救措施。
    NCCU Institutional Repository is made to protect the interests of copyright owners. If you believe that any material on the website infringes copyright, please contact our staff(nccur@nccu.edu.tw). We will remove the work from the repository and investigate your claim.
    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈