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    Please use this identifier to cite or link to this item: https://nccur.lib.nccu.edu.tw/handle/140.119/65229

    Title: An expedient synthesis of honokiol and its analogues as potential neuropreventive agents
    Authors: Tripathi, Subhankar;Chan, Ming-Huan;Chen, Chinpiao
    Contributors: 神科所
    Keywords: Honokiol;Neuropreventive;Parkinson’s disease;Suzuki–Miyaura cross coupling;Claisen rearrangement
    Date: 2012.01
    Issue Date: 2014-04-09 17:17:29 (UTC+8)
    Abstract: An efficient synthesis of honokiol with Suzuki–Miyaura cross coupling obtained an overall yield of 45%. The proposed approach successfully synthesized several structurally similar alkyl, alkenyl and alkynyl analogues, seven of which showed potential neuropreventive activity against MPP+-induced and CHP/TBHP oxidative stress induced neuroblastoma cell death.
    Relation: Bioorg Med Chem Lett,22(1), 216-221
    Source URI: http://dx.doi.org/10.1016/j.bmcl.2011.11.030
    Data Type: article
    Appears in Collections:[神經科學研究所 ] 期刊論文

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