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    政大機構典藏 > 商學院 > 統計學系 > 期刊論文 >  Item 140.119/72088
    Please use this identifier to cite or link to this item: http://nccur.lib.nccu.edu.tw/handle/140.119/72088

    Title: Reproducibility of microarray data: a further analysis of microarray quality control (MAQC) data
    Authors: Chen,James J.;Hsueh, Huey-Miin;Delongchamp, Robert R;Lin, Chien-Ju;Tsai, Chen-An
    Contributors: 統計系
    Date: 2007-10
    Issue Date: 2014-12-16 10:38:52 (UTC+8)
    Abstract: Many researchers are concerned with the comparability and reliability of microarray gene expression data. Recent completion of the MicroArray Quality Control (MAQC) project provides a unique opportunity to assess reproducibility across multiple sites and the comparability across multiple platforms. The MAQC analysis presented for the conclusion of inter- and intra-platform comparability/reproducibility of microarray gene expression measurements is inadequate. We evaluate the reproducibility/comparability of the MAQC data for 12901 common genes in four titration samples generated from five high-density one-color microarray platforms and the TaqMan technology. We discuss some of the problems with the use of correlation coefficient as metric to evaluate the inter- and intra-platform reproducibility and the percent of overlapping genes (POG) as a measure for evaluation of a gene selection procedure by MAQC.
    Relation: BMC Bioinformatics. 2007; 8: 412.
    Data Type: article
    DOI 連結: http://dx.doi.org/10.1186/1471-2105-8-412
    DOI: 10.1186/1471-2105-8-412
    Appears in Collections:[統計學系] 期刊論文

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