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题名:	Resting state glutamate predicts elevated pre-stimulus alpha during self-relatedness – A combined EEG-MRS study on rest-self overlap.
作者:	顏乃欣 Yen, Nai-Shing;Tsai, Shang-Yueh;Northoff, Georg
贡献者:	心理系
日期:	2015
上传时间:	2015-11-10 16:08:38 (UTC+8)
摘要:	Recent studies have demonstrated neural overlap between resting state activity and self-referential processing. This "rest-self" overlap occurs especially in anterior cortical midline structures like the perigenual anterior cingulate cortex (PACC). However, the exact neurotemporal and biochemical mechanisms remain to be identified. Therefore, we conducted a combined electroencephalography (EEG)-magnetic resonance spectroscopy (MRS) study. EEG focused on pre-stimulus (e.g., prior to stimulus presentation or perception) power changes to assess the degree to which those changes can predict subjects` perception (and judgment) of subsequent stimuli as high or low self-related. MRS measured resting state concentration of glutamate, focusing on PACC. High pre-stimulus (e.g., prior to stimulus presentation or perception) alpha power significantly correlated with both perception of stimuli judged to be highly self-related and with resting state glutamate concentrations in the PACC. In sum, our results show (i) pre-stimulus (e.g., prior to stimulus presentation or perception) alpha power and resting state glutamate concentration to mediate rest-self overlap that (ii) dispose or incline subjects to assign high degrees of self-relatedness to perceptual stimuli.
關聯:	Social Neuroscience
数据类型:	article
DOI 連結:	http://dx.doi.org/10.1080/17470919.2015.1072582
DOI:	10.1080/17470919.2015.1072582
显示于类别:	[心理學系] 期刊論文

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