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Introduction:
生命科學是本世紀科學界的大宗顯學,它的發展趨勢深具跨領域的整合性及影響力。其中尤以神經科學的研究影響層面近十年來急驟擴大,神經科學在生命科學領域中與其它學科的研究正快速的融合中。為此,本校於96年8月成立生命科學研究所,並獲教育部同意,自98學年度起正式更名為神經科學研究所。現階段發展以分子細胞神經科學為主軸,研究重點在於探討神經可塑性到學習記憶的機制。
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Items for Author "詹銘煥"
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[神經科學研究所] 會議論文
2022-06
Extracellular calcium and calcium channel modulators alter aminoglycoside-induced hair cell loss in zebrafish
詹銘煥 ; Chan, Ming-Huan
[神經科學研究所] 期刊論文
2018
Protective and therapeutic activity of honokiol in reversing motor deficits and neuronal degeneration in the mouse model of Parkinson’s disease
詹銘煥 ; Chen, Hwei-Hsien ; Chang, Pei-Chi ; Chen, Chinpiao ; Chan, Ming-Huan
[神經科學研究所] 期刊論文
2013-02
Honokiol Blocks Store Operated Calcium Entry in CHO Cells Expressing the M3 Muscarinic Receptor: Honokiol and Muscarinic Signaling
詹銘煥 ; Chan,Ming-Huan
[神經科學研究所] 期刊論文
2017-03
Quantitative analysis of the therapeutic effect of magnolol on MPTP-induced mouse model of Parkinson`s disease using in vivo18 F-9-fluoropropyl-(+)-dihydrotetrabenazine PET imaging
Weng, Chi-Chang ; Chen, Zi-An ; Chao, Ko-Ting ; Ee, Ting-Wei ; Lin, Kun-Ju ; Chan, Ming-Huan ; Hsiao, Ing-Tsung ; Yen, Tzu-Chen ; Kung, Mei-Ping ; Hsu, Ching-Han ; Wey, Shiaw-Pyng ; 詹銘煥
[神經科學研究所] 期刊論文
2017-03
Quantitative analysis of the therapeutic effect of magnolol on MPTP-induced mouse model of Parkinson’s disease using in vivo 18F-9-fluoropropyl-(+)-dihydrotetrabenazine PET imaging.
詹銘煥 ; Weng, Chi-Chang ; Chen, Zi-An ; Chao, Ko-Ting ; Ee, Ting-Wei ; Lin, Kun-Ju ; Chan, Ming-Huan ; Hsiao, Ing-Tsung ; Yen, Tzu-Chen ; Kung, Mei-Ping
[神經科學研究所] 期刊論文
2020-06
Effectiveness in the block by honokiol. A dimerized allylphenol from Magnonia officinalis, of Hyperpolarization-activated cation current and delayed-rectifier K current
詹銘煥 ; Chan, Ming-Huan ; Chen, Hwei-Hsien ; Lo, Yi-Ching ; Wu, Sheng-Nan
[神經科學研究所] 國科會研究計畫
2014
神經恢復性藥物治療帕金森氏症之研發
詹銘煥
[神經科學研究所] 期刊論文
2009-01
Astrgaloside IV increases MMP-2 mRNA and protein expression in human lung cancer A549 cells.
Su, Chin-Cheng ; Chiou, Tsrong-Laang ; Chan, Ming-Huan ; Lin, Jaung-Geng ; 詹銘煥
[神經科學研究所] 期刊論文
2020-12
Increased behavioral and neuronal responses to a hallucinogenic drug after adolescent toluene exposure in mice: effects of antipsychotic treatment
詹銘煥 ; Chan, Ming-Huan ; Mei-YiLee ; Bih-FenLin ; Hwei-HsienChen
[神經科學研究所] 期刊論文
2013-01
Magnolia Polyphenols Attenuate Oxidative and Inflammatory Responses in Neurons and Microglial Cells
詹銘煥 ; Chuang,Dennis Y ; Chan,Ming-Huan ; Zong,Yijia ; Sheng,Wenwen ; He,Yan ; Jiang,Jing Hua ; Simonyi,Agnes ; Gu,Zezong ; Fritsche,Kevin L ; Cui, Jiankun ; Lee,James C ; Folk, William R ; Lubahn,Dennis B ; Sun,Albert Y ; Sun,Grace Y
[神經科學研究所] 期刊論文
2020-12
N,Ndimethylglycine prevents toluene-induced impairment in recognition memory and synaptic plasticity in mice
詹銘煥 ; Chan, Ming-Huan ; Chung-PinHsieh ; HaoChen ; LinyiChen ; Hwei-HsienChen
[神經科學研究所] 期刊論文
2013-11
Methamphetamine inhibits voltage-gated potassium currents in NG108-15 cells: Possible contribution of large-conductance calcium-activated potassium channels
Wang, Ya-Jean ; Chan, Ming-Huan ; Chen, Hwei-Hisen ; 詹銘煥
[神經科學研究所] 期刊論文
2011-02
mGluR5 positive modulators both potentiate activation and restore inhibition in NMDA receptors by PKC dependent pathway
Chen, Hwei-Hsien ; Liao, Pei-Fei ; Chan, Ming-Huan ; 詹銘煥
[神經科學研究所] 期刊論文
2013-01
Cellular Internalization of Quantum Dots Mediated by Cell-Penetrating
詹銘煥 ; Chan,Ming-Huan ; Liu,Betty Revon ; Chiang,Huey-Jenn ; Huang,Yue-Wern ; Chan,Ming-Huan ; Chen,Hwei-Hsien ; Lee,Han-Jung
[神經科學研究所] 期刊論文
Antinociceptive actions of honokiol and magnolol on glutamatergic and inflammatory pain
YR Lin ; HH Chen ; YC Lin ; CH Ko ; MH Chan ; 詹銘煥
[神經科學研究所] 期刊論文
2014-10
Long-lasting alterations in 5-HT2A receptor after a binge regimen of methamphetamine in mice
詹銘煥 ; Chiu, Hong-Yi ; Chan, Ming-Huan ; Lee, Mei-Yi ; Chen, Shao-Tsu ; Zhan, Zih-Yi ; Chen, Hwei-Hsien
[神經科學研究所] 期刊論文
2012-02
A gene delivery system for insect cells mediated by arginine-rich cell-penetrating peptides
Chen, Yung-Jen ; Liu, Betty Revon ; Dai, Yun-Hao ; Lee, Cheng-Yi ; Chan, Ming-Huan ; Chen, Hwei-Hsien ; Chiang, Huey-Jenn ; Lee, Han-Jung ; 詹銘煥
[神經科學研究所] 期刊論文
2014-02
N-acetylcysteine modulates hallucinogenic 5-HT2A receptor agonist-mediated responses: Behavior, molecular, and electrophysiological studies.
Lee, Mei-Yi ; Chiang, Chun-Cheng ; Chiu, Hong-Yi ; Chan, Ming-Huan ; Chen, Hwei-Hsien ; 詹銘煥
[神經科學研究所] 期刊論文
2012-01
An expedient synthesis of honokiol and its analogues as potential neuropreventive agents
Tripathi, Subhankar ; Chan, Ming-Huan ; Chen, Chinpiao ; 詹銘煥
[神經科學研究所] 期刊論文
2018-12
Therapeutic effects of honokiol on motor impairment in hemiparkinsonian mice are associated with reversing neurodegeneration and targeting PPARr regulation
Chen, Hwei-Hsien ; Chang, Pei-Chi ; Wey, Shiaw-Pyng ; Chen, Pei-Mei ; Chen, Chinpiao ; Chan, Ming-Huan ; 詹銘煥 ; Chan, Ming-Huan
[神經科學研究所] 期刊論文
2016-09
Betaine enhances antidepressant-like, but blocks psychotomimetic effects of ketamine in mice
詹銘煥 ; Lin, Jen-Cheng ; Lee, Mei-Yi ; Chan, Ming-Huan ; Chen, Yi-Chyan ; Chen, Hwei-Hsien
[神經科學研究所] 期刊論文
2011-09
Toluene exposure during brain growth spurt and adolescence produces differential effects on N-methyl-d-aspartate receptor-mediated currents in rat hippocampus
Chen, Hwei-Hsien ; Lin, Yi-Ruu ; Chan, Ming-Huan ; 詹銘煥
[神經科學研究所] 期刊論文
2018-09
Attenuation of toluene-induced brain stimulation reward enhancement and behavioral disturbances by N-acetylcysteine in mice
Wu, Chia-Yen ; Tsai, Yi-Lin ; Hsieh, Chung-Pin ; Wang, Tsui Chin ; 詹銘煥 ; Chan, Ming-Huan ; Chen, Hwei-Hsien
[神經科學研究所] 期刊論文
2012-12
Metabotropic glutamate receptor 5 modulates behavioral and hypothermic responses to toluene in rats
Chan, Ming-Huan ; Lee, Chia-Chi ; Lin, Bih-Fen ; Wu, Chia-Yen ; Chen, Hwei-Hsien ; 詹銘煥
[神經科學研究所] 期刊論文
2012-12
Sarcosine attenuates toluene-induced motor incoordination, memory impairment, and hypothermia but not brain stimulation reward enhancement in mice
詹銘煥 ; Chan, Ming-Huan ; Chung, Shiang-Sheng ; Stoker, Astrid K. ; Markou, Athina ; Chen, Hwei-Hsien
[神經科學研究所] 專書/專書篇章
2013-09
Effects of surface charge and particle size of cell-penetrating peptide/nanoparticle complexes on cellular internalization.
Liu, Betty Revon ; Chan, Ming-Huan ; Chen, Hwei-Hsien ; Lo, Shih-Yen ; Huang, Yue-Wern ; Lee, Han-Jung ; 詹銘煥
[神經科學研究所] 期刊論文
2012-01
Honokiol Suppresses the Development of Post-ischemic Glucose Intolerance and Neuronal Damage in Mice
詹銘煥 ; Chan,Ming-Huan ; Shinichi Harada ; Maya Kishimoto ; Mana Kobayashi ; Kazuo Nakamoto ; Wakako Fujita-Hamabe ; Chen,Hwei-Hsien ; Chan,Ming-Huan ; Shogo Tokuyama
[神經科學研究所] 期刊論文
2018-08
Protective and therapeutic activity of honokiol in reversing motor deficits and neuronal degeneration in the mouse model of Parkinson’s disease
Chen, Hwei-Hsien ; Chang, Pei-Chi ; 詹銘煥 ; Chen, Chin-piao ; Chan, Ming-Huan
[神經科學研究所] 期刊論文
2016-11
N,N-dimethylglycine differentially modulates psychotomimetic and antidepressant-like effects of ketamine in mice
詹銘煥 ; Lin, Jen-Cheng ; Chan, Ming-Huan ; Lee, Mei-Yi ; Chen, Yi-Chyan ; Chen, Hwei-Hsien
[神經科學研究所] 期刊論文
2021-07
Differential inhibitory effects of resveratrol on excitotoxicity and synaptic plasticity: involvement of NMDA receptor subtypes
詹銘煥 ; Chan, Ming-Huan ; Hsieh, Chung-Pin ; Chang, Wei-Tang ; Chen, Linyi ; Chen, Hwei-Hsien
[神經科學研究所] 期刊論文
2012-04
Inhibition of glycogen synthase kinase-3 attenuates psychotomimetic effects of ketamine
Chan, Ming-Huan ; Chiu, Pao-Hsiang ; Lin, Chia-Yu ; Chen, Hwei-Hsien ; 詹銘煥
[神經科學研究所] 期刊論文
2012-04
Inhibition of glycogen synthase kinase-3 attenuates psychotomimetic effects of ketamine.
詹銘煥 ; Chan, Ming-Huan
[神經科學研究所] 期刊論文
2016-05
Resveratrol attenuates cortical neuron activity: roles of large conductance calcium-activated potassium channels and voltage-gated sodium channels
詹銘煥 ; Wang, Ya-Jean ; Chan, Ming-Huan ; Chen, Linyi ; Wu, Sheng-Nan ; Chen, Hwei-Hisen
[神經科學研究所] 期刊論文
2017
Stimulatory actions of a novel thiourea derivative on large-conductance, calcium-activated potassium channels
Wu, Sheng‐Nan ; Chern, Jyh‐Haur ; Shen, Santai ; Chen, Hwei‐Hisen ; Hsu, Ying‐Ting ; Lee, Chih‐Chin ; Chan, Ming‐Huan ; Lai, Ming‐Chi ; Shie, Feng‐Shiun ; 詹銘煥
[神經科學研究所] 期刊論文
2017-12
Effect of Pachybasin on General Toxicity and Developmental Toxicity in Vivo
Lin, Yi-Ruu ; Peng, Kou-Cheng ; Chan, Ming-Huan ; Peng, Huan-Lin ; Liu, Shu-Ying ; 詹銘煥 ; Chan, Ming-Huan
[神經科學研究所] 期刊論文
2021-12
Betaine prevents and reverses the behavioral deficits and synaptic dysfunction induced by repeated ketamine exposure in mice
詹銘煥 ; Chan, Ming-Huan ; Chen, Shao-Tsu ; Hsieh, Chung-Pin ; Lee, Mei-Yi ; Chen, Liao-Chen ; Huang, Chien-Min ; Chen, Hwei-Hsien
[神經科學研究所] 期刊論文
2021-10
Betaine supplementation to rats alleviates disturbances induced by high-fat diet: pleiotropic effects in model of type 2 diabetes
詹銘煥 ; Chan, Ming-Huan ; Szkudelska, K. ; Okulicz, M. ; Jasaszwili, M. ; Lukomska, A. ; Malek, E. ; Shah, M. ; Sunder, S . ; Szkudelski, T.
[神經科學研究所] 期刊論文
2021-09
N, N-dimethylglycine Protects Behavioral Disturbances and Synaptic Deficits Induced by Repeated Ketamine Exposure in Mice
詹銘煥 ; Chan, Ming-Huan ; Hsieh, Chung-Pin ; Chen, Shao-Tsu ; Lee, Mei-Yi ; Huang, Chieh-Min ; Chen, Hwei-Hsien
[神經科學研究所] 會議論文
2019-10
Combined treatment with dimethylglycine attenuates the behavioral deficits induced by repeated ketamine exposure
詹銘煥 ; Chan, Ming-Huan
[神經科學研究所] 會議論文
2018-03
NMDA Receptor Modulator Rescues Psychiatric Phenotypes in Mouse Model of Maternal Immune Activation
陳紹寬 ; Chen, Shau-Kwaun ; 洪筠婷 ; 張家銘 ; 邱筱涵 ; 詹銘煥 ; Hung, Yun Ting ; Chang, Jia Ming ; Chiu, Hsiao Han ; Chan, Ming Huan
[神經科學研究所] 期刊論文
2022-11
Beneficial effects of atypical antipsychotics on object recognition deficits after adolescent toluene exposure in mice: involvement of 5-HT1A receptors
詹銘煥 ; Chan, Ming-Huan ; Lee, Mei-Yi ; Hsieh, Chung-Pin ; Chen, Hwei-Hsien
[神經科學研究所] 期刊論文
2022-11
L-4-Fluorophenylglycine produces antidepressant-like effects and enhances resilience to stress in mice
詹銘煥 ; Chan, Ming-Huan ; Sung, Che-Wei ; Chang, Wei-Tang ; Kuo, Tsung-Han ; Chen, Hwei-Hsien
[神經科學研究所] 會議論文
2022-11
The analgesic mechanisms of trimethylglycine on cisplatin-induced neuropathic pain in mice
詹銘煥 ; Chan, M.-H. ; Luo, Y.-Z. ; Hung, Y.-T. ; Chen, H.-H.
[神經科學研究所] 期刊論文
2023-05
NMDA receptor glycine binding site modulators for prevention and treatment of ketamine use disorder
詹銘煥 ; Chan, Ming-Huan ; Hsiao, Yu-Chin ; Lee, Mei-Yi ; Chen, Hwei-Hsien
[神經科學研究所] 會議論文
2023-07
2-Fluorodeschloroketamine shares a similar pharmacological and behavioral profiles with ketamine in vitro and in vivo studies
詹銘煥
[神經科學研究所] 專書/專書篇章
2013
Protein transduction in human cellsmediated by arginine-richcell-penetrating peptides in mixedcovalent and noncovalent manners
Liu, B.R. ; Chan, Ming-huan ; Chen, H.-H. ; Huang, Y.-W. ; Lee, H.-J. ; 詹銘煥
[神經科學研究所] 期刊論文
2011-04
Protective and restorative effects of magnolol on neurotoxicity in mice with 6-hydroxydopamine-induced hemiparkinsonism
詹銘煥 ; Lin,Shiau-Chin ; Chen,Hwei-Hsien ; Chan,Ming-Huan
[神經科學研究所] 國科會研究計畫
2011
探討厚朴多酚環治療帕金森氏症之抗發炎及氧化壓力機制(I)
詹銘煥
[神經科學研究所] 國科會研究計畫
2012
探討厚朴多酚環治療帕金森氏症之抗發炎及氧化壓力機制(II)
詹銘煥
[神經科學研究所] 國科會研究計畫
2013
探討厚朴多酚環治療帕金森氏症之抗發炎及氧化壓力機制(III)
詹銘煥
[神經科學研究所] 期刊論文
2015-03
Protective role of L-ascorbic acid, N-acetylcysteine and apocynin on neomycin-induced hair cell loss in Zebrafish
Wu, C.-Y. ; Lee, H.-J. ; Liu, C.-F. ; Korivi, M. ; Chen, H.-H. ; Chan, Ming-Huan ; 詹銘煥
[神經科學研究所] 期刊論文
2015-06
The group II metabotropic glutamate receptor agonist LY379268 reduces toluene-induced enhancement of brain-stimulation reward and behavioral disturbances
Chan, Ming-Huan ; Tsai, Yi-Ling ; Lee, Mei-Yi ; Stoker, Astrid ; Markou, K. Athina ; Chen, Hwei-Hsien ; 詹銘煥 ; 蔡依玲
[神經科學研究所] 期刊論文
2016-10
Extracellular calcium concentration and channel activity involved in aminoglycoside-induced hair cell toxicity in the zebrafish lateral line
詹銘煥 ; CHAN, MING-HUAN ; Wu, C.Y. ; Liu, C.F. ; Chen, H.H.